Publications

2023

A. Shen, K. Hencel, M. T. Parker, R. Scott, R. Skukan, A. S. Adesina, C. L. Metheringham, E. A. Miska, Y. Nam, W. Haerty, G. G. Simpson, A. Akay. U6 snRNA m6A modification is required for accurate and efficient cis- and trans-splicing of C. elegans mRNAs. bioRxiv (2023), doi:10.1101/2023.09.16.558044.

2021

Berkyurek, A. C., Furlan, G., Lampersberger, L., Beltran, T., Weick, E.-M., Nischwitz, E., Cunha Navarro, I., Braukmann, F., Akay, A., Price, J., Butter, F., Sarkies, P. & Miska, E. A. The RNA polymerase II subunit RPB-9 recruits the integrator complex to terminate Caenorhabditis elegans piRNA transcription. EMBO J.40, e105565 (2021).

Kranse, O., Beasley, H., Adams, S., Pires-daSilva, A., Bell, C., Lilley, C. J., Urwin, P. E., Bird, D., Miska, E., Smant, G., Gheysen, G., Jones, J., Viney, M., Abad, P., Maier, T. R., Baum, T. J., Siddique, S., Williamson, V., Akay, A. & Eves-van den Akker, S. Toward genetic modification of plant-parasitic nematodes: delivery of macromolecules to adults and expression of exogenous mRNA in second stage juveniles. G3 11, (2021).

Navarro, I. C., Tuorto, F., Jordan, D., Legrand, C., Price, J., Braukmann, F., Hendrick, A. G., Akay, A., Kotter, A., Helm, M., Lyko, F. & Miska, E. A. Translational adaptation to heat stress is mediated by RNA 5-methylcytosine in Caenorhabditis elegans. EMBO J.40, e105496 (2021).

2020

Suen, K. M., Braukmann, F., Butler, R., Bensaddek, D., Akay, A., Lin, C.-C., Milonaitytė, D., Doshi, N., Sapetschnig, A., Lamond, A., Ladbury, J. E. & Miska, E. A. DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans. Nat. Commun.11, 4242 (2020).

2019

Akay, A., Jordan, D., Navarro, I. C., Wrzesinski, T., Ponting, C. P., Miska, E. A. & Haerty, W. Identification of functional long non-coding RNAs in C. elegans. BMC Biol.17, 14 (2019).

2018

Sarabipour, S., Wissink, E. M., Burgess, S. J., Hensel, Z., Debat, H., Emmott, E., Akay, A., Akdemir, K. & Schwessinger, B. Maintaining confidence in the reporting of scientific outputs. (PeerJ Preprints, 2018). doi:10.7287/peerj.preprints.27098v1

S Sarabipour, EM Wissink, SJ Burgess, Z Hensel, H Debat, E Emmott, A Akay, KC Akdemir, B Schwessinger. Preprints are good for science and good for the public. Nature560, 553 (2018).

2017

Akay, A., Di Domenico, T., Suen, K. M., Nabih, A., Parada, G. E., Larance, M., Medhi, R., Berkyurek, A. C., Zhang, X., Wedeles, C. J., Rudolph, K. L. M., Engelhardt, J., Hemberg, M., Ma, P., Lamond, A. I., Claycomb, J. M. & Miska, E. A. The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription. Dev. Cell42, 241–255.e6 (2017).

van Delft, P.*, Akay, A.*, Huber, S. M.*, Bueschl, C., Rudolph, K. L. M., Di Domenico, T., Schuhmacher, R., Miska, E. A. & Balasubramanian, S. The Profile and Dynamics of RNA Modifications in Animals. Chembiochem18, 979–984 (2017).

2015

Akay, A., Sarkies, P. & Miska, E. A. E. coli OxyS non-coding RNA does not trigger RNAi in C. elegans. Sci. Rep.5, 9597 (2015).

2013

Gartner, A. & Akay, A. Stress response: anything that doesn’t kill you makes you stronger. Curr. Biol. (2013). at <https://www.sciencedirect.com/science/article/pii/S0960982213011834>

Akay, A., Craig, A., Lehrbach, N., Larance, M., Pourkarimi, E., Wright, J. E., Lamond, A., Miska, E. & Gartner, A. RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans. Open Biol.3, 130151 (2013).

2008

Feitsma, H., Akay, A. & Cuppen, E. Alkylation damage causes MMR-dependent chromosomal instability in vertebrate embryos. Nucleic Acids Res.36, 4047–4056 (2008).